chenkaijie@csmspharm.com
Boc-Tyr(OtBu)-Aib-Gln(Trt)-Gly-OH (CAS: 2612237-79-1) is used in the synthesis of GLP-1 analogs, where it serves as a building block to incorporate specific amino acids into the peptide chain with strategic protection groups to ensure controlled and efficient synthesis. The presence of tyrosine, Aib (α-aminoisobutyric acid), glutamine, and glycine, along with protecting groups like OtBu (tert-butyl) on tyrosine and Trt (trityl) on glutamine, allows for the creation of complex peptide structures that are essential for the development of stable and effective GLP-1 receptor agonists. These modifications can enhance the stability, bioavailability, and receptor binding affinity of the final GLP-1 analogs, which are crucial for their therapeutic efficacy in treating type 2 diabetes and obesity.
High Purity and Content: individual impurity < 0.1%.
GMP-Compliant Manufacturing: manufactured and released by an GMP-certified API facility. Large production capacity, exceeding 100 kilograms per batch.
Comprehensive Quality Studies: able to perform comprehensive quality studies according to the client's requirements, including related substances, residual solvents, genotoxic impurities, inorganic impurities, structure identification, and stability testing, etc. All the methods are well validated and can be transferred to clients. The related impurity references can also be provided.
| Catalog Number | LK0092 |
|---|---|
| Purity | 99.7% |
| Molecular Formula | C48H59N5O9 |
| Physical State |
White or Off-white Solid |
| Storage | Recommended storage temperature: -20℃, Keep refrigerated and sealed. |
| Molecular Weight | 850.03 |
| CAS NO. | 2612237-79-1 |
![Fmoc-L-Lys[C20-OtBu-γ-Glu(OtBu)-AEEA]-OH](/static/img/product/JPG/LK0059.jpg)
| Code | Phrase |
|---|---|
| P101 | If medical advice is needed, have product container or label at hand. |
| P102 | Keep out of reach of children. |
| P103 | Read label before use. |
| Code | Phrase |
|---|---|
| P201 | Obtain special instructions before use. |
| P202 | Do not handle until all safety precautions have been read and understood. |
| P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
| P211 | Do not spray on an open flame or other ignition source. |
| P220 | Keep/Store away from clothing/combustible materials. |
| P221 | Take any precaution to avoid mixing with combustibles. |
| P222 | Do not allow contact with air. |
| P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
| Code | Phrase |
|---|---|
| P301+P310 | If swallowed: Immediately call a poison center or doctor. |
| P303+P361+P353 | If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. |
| P304+P340 | If inhaled: Remove person to fresh air and keep comfortable for breathing. |
| P305+P351+P338 | If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P310 | Immediately call a poison center or doctor. |
| Code | Phrase |
|---|---|
| P403+P233 | Store in a well-ventilated place. Keep container tightly closed. |
| P405 | Store locked up. |
| P406 | Store in corrosive resistant/container with a resistant inner liner. |
| Code | Phrase |
|---|---|
| P501 | Dispose of contents/container to an approved waste disposal plant. |
| Code | Phrase |
|---|---|
| P101 | If medical advice is needed, have product container or label at hand. |
| P102 | Keep out of reach of children. |
| P103 | Read label before use. |
| Code | Phrase |
|---|---|
| P201 | Obtain special instructions before use. |
| P202 | Do not handle until all safety precautions have been read and understood. |
| P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
| P211 | Do not spray on an open flame or other ignition source. |
| P220 | Keep/Store away from clothing/combustible materials. |
| P221 | Take any precaution to avoid mixing with combustibles. |
| P222 | Do not allow contact with air. |
| P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
| Code | Phrase |
|---|---|
| P301+P310 | If swallowed: Immediately call a poison center or doctor. |
| P303+P361+P353 | If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. |
| P304+P340 | If inhaled: Remove person to fresh air and keep comfortable for breathing. |
| P305+P351+P338 | If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P310 | Immediately call a poison center or doctor. |
| Code | Phrase |
|---|---|
| P403+P233 | Store in a well-ventilated place. Keep container tightly closed. |
| P405 | Store locked up. |
| P406 | Store in corrosive resistant/container with a resistant inner liner. |
| Code | Phrase |
|---|---|
| P501 | Dispose of contents/container to an approved waste disposal plant. |