EMAIL

luohuichao@csmspharm.com

Call Now

(+86) 189 7583 2125

Contact
1890228-73-5
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Overview
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
CAS: 1890228-73-5
Cat. No. : LK0063
M. W. : 824.98
Synonyms: Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH；Boc-L-His(Trt)-Aib-Glu(OtBu)-Gly-OH；Boc-His(Trt)-Aib-Glu(tBu)-Gly-OH；Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH；Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH Boc-His(Trt)-Aib-Glu(OBtu)-Gly-OH；Boc-His(Trt)-Aib-Glu(OtBU) Gly-ОH
IUPAC Name: 2-[[(2S)-2-[[2-methyl-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(1-tritylimidazol-4-yl)propanoyl]amino]propanoyl]amino]-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoyl]amino]acetic acid
InChIKey: OCRJCXTZCKCRBO-KVZPBDITNA-N
SMILES: O=C(O)CNC([C@@H](NC(C(C)(NC([C@@H](NC(OC(C)(C)C)=O)CC1=CN(C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C=N1)=O)C)=O)CCC(OC(C)(C)C)=O)=O
PDF:
Purity: ≥ 98.0%/nAppearance: white or off-white solid/nStorage conditions: sealed, refrigerated (2~8℃)
Product Use

Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH (CAS: 1890228-73-5), as a part of main chain of semaglutide, can be used as a starting material for the synthesis of semaglutide, this product inserts histidine, modified amino acids (alanine → α-aminoisobutyric acid, resistant to DPP-4 degradation), glutamic acid, and glycine at the 7th, 8th, 9th, and 10th positions of semaglutide, respectively.

Product Specification

Excellent Morphological Properties: white or kind of white powder./nHigh Purity and Content: individual impurity < 0.1%./nGMP-Compliant Manufacturing: manufactured and released by an GMP-certified API facility. Large production capacity, exceeding 100 kilograms per batch./nComprehensive Quality Studies: able to perform comprehensive quality studies according to the client's requirements, including related substances, residual solvents, genotoxic impurities, inorganic impurities, structure identification, and stability testing, etc. All the methods are well validated and can be transferred to clients. The related impurity references can also be provided.

General Information
Product Number LK0063
Purity ≥ 98.0%
Molecular Formula C45H56N6O9
Physical State white or off-white solid
Storage Recommended storage temperature: -20C, Keep refni gerated and sealed.
Molecular Weight 824.98
CAS RN 1890228-73-5
Product Relate
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
1662688-20-1
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Ste-γ-Glu-AEEA-AEEA-OSU
1169630-40-3
Ste-γ-Glu-AEEA-AEEA-OSU
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu
1118767-16-0
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu
Fmoc-His-Aib-OH
1446013-07-5
Fmoc-His-Aib-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
1890228-73-5
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH

© 2024 ChangshaMorning Shine Co., LTD, All rights reserved.

×
GHS Precautionary Statements
Precautionary Statements-General
CodePhrase
P101If medical advice is needed, have product container or label at hand.
P102Keep out of reach of children.
P103Read label before use.
Prevention
CodePhrase
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211Do not spray on an open flame or other ignition source.
P220Keep/Store away from clothing/combustible materials.
P221Take any precaution to avoid mixing with combustibles.
P222Do not allow contact with air.
P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.
Response
CodePhrase
P301+P310If swallowed: Immediately call a poison center or doctor.
P303+P361+P353If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310Immediately call a poison center or doctor.
Storage
CodePhrase
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P406Store in corrosive resistant/container with a resistant inner liner.
Disposal
CodePhrase
P501Dispose of contents/container to an approved waste disposal plant.
×
GHS Precautionary Statements
Precautionary Statements-General
CodePhrase
P101If medical advice is needed, have product container or label at hand.
P102Keep out of reach of children.
P103Read label before use.
Prevention
CodePhrase
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211Do not spray on an open flame or other ignition source.
P220Keep/Store away from clothing/combustible materials.
P221Take any precaution to avoid mixing with combustibles.
P222Do not allow contact with air.
P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.
Response
CodePhrase
P301+P310If swallowed: Immediately call a poison center or doctor.
P303+P361+P353If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310Immediately call a poison center or doctor.
Storage
CodePhrase
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P406Store in corrosive resistant/container with a resistant inner liner.
Disposal
CodePhrase
P501Dispose of contents/container to an approved waste disposal plant.