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1662688-20-1
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Overview
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
CAS: 1662688-20-1
Cat. No. : LK0053
M. W. : 1196.51
Synonyms: Fmoc-Lys(tBuOCO-(CH2)16-CO-Glu(AEEA-AEEA)-OtBu)-OH
IUPAC Name: (23S,50S)-50-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-23-(tert-butoxycarbonyl)-2,2-dimethyl-4,21,26,35,44-pentaoxo-3,30,33,39,42-pentaoxa-22,27,36,45-tetraazahenpentacontan-51-oic acid
InChIKey: COTQASXXEXJBOM-PJYGOTMFSA-N
SMILES: O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@@H](CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O)=O)C(OC(C)(C)C)=O)=O)=O)=O)C(O)=O
PDF:
Purity: ≥ 98.0%/nAppearance: white to brown semisolid or solid/nStorage conditions: sealed, frozen (-20℃ ± 5℃)
Product Use

Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH (CAS：1662688-20-1), as the side chain of semaglutide, can be used in the solid-phase synthesis of semaglutide, and Ste-γ-Glu-AEEA-AEEA-OSU (CAS: 1169630-40-3) can be used in the semi-synthetic recombinant fermentation process of semaglutide.

Product Specification

Excellent Morphological Properties: White to light yellow solid particles with good flowability./nHigh Purity: Individual impurity < 0.1%./nGMP-Compliant Manufacturing: manufactured and released by an GMP-certified API facility./nComprehensive Quality Studies: able to perform comprehensive quality studies according to the client's requirements, including related substances, residual solvents, genotoxic impurities, inorganic impurities, structure identification, and stability testing, etc. All the methods are well validated and can be transferred to clients. The related impurity references can also be provided.

General Information
Safety & Regulations
Product Number LK0053
Purity ≥ 98.0%
Molecular Formula C64H101N5O16
Physical State Form: Solid or semi-solid Color: White to Light Brown
Storage Recommended storage temperature: -20C, Keep refni gerated and sealed.
Molecular Weight 1196.51
CAS RN 1662688-20-1
GHS Pictogram Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Signal Word Warning
Hazard Statements H413 (100%)
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GHS Hazard Statements
Precautionary Statements P273, and P501
×
GHS Precautionary Statements
Product Relate
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
1662688-20-1
Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH
Ste-γ-Glu-AEEA-AEEA-OSU
1169630-40-3
Ste-γ-Glu-AEEA-AEEA-OSU
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu
1118767-16-0
tBuO-Ste-γ-Glu(AEEA-AEEA-OH)-OtBu
Fmoc-His-Aib-OH
1446013-07-5
Fmoc-His-Aib-OH
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH
1890228-73-5
Boc-His(Trt)-Aib-Glu(OtBu)-Gly-OH

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GHS Precautionary Statements
Precautionary Statements-General
CodePhrase
P101If medical advice is needed, have product container or label at hand.
P102Keep out of reach of children.
P103Read label before use.
Prevention
CodePhrase
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211Do not spray on an open flame or other ignition source.
P220Keep/Store away from clothing/combustible materials.
P221Take any precaution to avoid mixing with combustibles.
P222Do not allow contact with air.
P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.
Response
CodePhrase
P301+P310If swallowed: Immediately call a poison center or doctor.
P303+P361+P353If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310Immediately call a poison center or doctor.
Storage
CodePhrase
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P406Store in corrosive resistant/container with a resistant inner liner.
Disposal
CodePhrase
P501Dispose of contents/container to an approved waste disposal plant.
×
GHS Precautionary Statements
Precautionary Statements-General
CodePhrase
P101If medical advice is needed, have product container or label at hand.
P102Keep out of reach of children.
P103Read label before use.
Prevention
CodePhrase
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P211Do not spray on an open flame or other ignition source.
P220Keep/Store away from clothing/combustible materials.
P221Take any precaution to avoid mixing with combustibles.
P222Do not allow contact with air.
P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.
Response
CodePhrase
P301+P310If swallowed: Immediately call a poison center or doctor.
P303+P361+P353If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310Immediately call a poison center or doctor.
Storage
CodePhrase
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P406Store in corrosive resistant/container with a resistant inner liner.
Disposal
CodePhrase
P501Dispose of contents/container to an approved waste disposal plant.