luohuichao@csmspharm.com
Fmoc-His-Aib-OH TFA (CAS: 1446013-08-6), as a part of main chain of semaglutide, can be used as a starting material for the synthesis of semaglutide, this product inserts histidine and modified amino acids (alanine → α-aminoisobutyric acid, resistant to DPP-4 degradation) at the 7th and 8th positions of semaglutide, respectively.
Excellent Morphological Properties: white or kind of white powder./nHigh Purity and Content: individual impurity < 0.1%./nGMP-Compliant Manufacturing: manufactured and released by an GMP-certified API facility. Large production capacity, exceeding 100 killograms per batch.\nComprehensive Quality Studies: able to perform comprehensive quality studies according to the client's requirements, including related substances, residual solvents, genotoxic impurities, inorganic impurities, structure identification, and stability testing, etc. All the methods are well validated and can be transferred to clients. The related impurity references can also be provided.
| Product Number | LK0066 |
|---|---|
| Purity | ≥ 99.0% |
| Molecular Formula | C27H27F3N4O7 |
| Physical State | Powder or crystals |
| Storage | Recommended storage temperature: -20C, Keep refni gerated and sealed. |
| Molecular Weight | 576.53 |
| CAS RN | 1446013-08-6 |
| GHS Pictogram |  |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318 (100%)
×
GHS Hazard Statements |
| Precautionary Statements |
P264+P265, P280, P305+P354+P338, and P317
×
GHS Precautionary Statements |
![Fmoc-L-Lys[Oct-(otBu)-γ-Glu-(otBu)-AEEA-AEEA]-OH](/static/img/product/semaglutide_intermediates/LK0053.png)
| Code | Phrase |
|---|---|
| P101 | If medical advice is needed, have product container or label at hand. |
| P102 | Keep out of reach of children. |
| P103 | Read label before use. |
| Code | Phrase |
|---|---|
| P201 | Obtain special instructions before use. |
| P202 | Do not handle until all safety precautions have been read and understood. |
| P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
| P211 | Do not spray on an open flame or other ignition source. |
| P220 | Keep/Store away from clothing/combustible materials. |
| P221 | Take any precaution to avoid mixing with combustibles. |
| P222 | Do not allow contact with air. |
| P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
| Code | Phrase |
|---|---|
| P301+P310 | If swallowed: Immediately call a poison center or doctor. |
| P303+P361+P353 | If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. |
| P304+P340 | If inhaled: Remove person to fresh air and keep comfortable for breathing. |
| P305+P351+P338 | If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P310 | Immediately call a poison center or doctor. |
| Code | Phrase |
|---|---|
| P403+P233 | Store in a well-ventilated place. Keep container tightly closed. |
| P405 | Store locked up. |
| P406 | Store in corrosive resistant/container with a resistant inner liner. |
| Code | Phrase |
|---|---|
| P501 | Dispose of contents/container to an approved waste disposal plant. |
| Code | Phrase |
|---|---|
| P101 | If medical advice is needed, have product container or label at hand. |
| P102 | Keep out of reach of children. |
| P103 | Read label before use. |
| Code | Phrase |
|---|---|
| P201 | Obtain special instructions before use. |
| P202 | Do not handle until all safety precautions have been read and understood. |
| P210 | Keep away from heat/sparks/open flames/hot surfaces. - No smoking. |
| P211 | Do not spray on an open flame or other ignition source. |
| P220 | Keep/Store away from clothing/combustible materials. |
| P221 | Take any precaution to avoid mixing with combustibles. |
| P222 | Do not allow contact with air. |
| P223 | Keep away from any possible contact with water, because of violent reaction and possible flash fire. |
| Code | Phrase |
|---|---|
| P301+P310 | If swallowed: Immediately call a poison center or doctor. |
| P303+P361+P353 | If on skin (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. |
| P304+P340 | If inhaled: Remove person to fresh air and keep comfortable for breathing. |
| P305+P351+P338 | If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| P310 | Immediately call a poison center or doctor. |
| Code | Phrase |
|---|---|
| P403+P233 | Store in a well-ventilated place. Keep container tightly closed. |
| P405 | Store locked up. |
| P406 | Store in corrosive resistant/container with a resistant inner liner. |
| Code | Phrase |
|---|---|
| P501 | Dispose of contents/container to an approved waste disposal plant. |