EMAIL

chenkaijie@csmspharm.com

Call Now

(+86) 199 7311 3652

1446013-08-6

Fmoc-His-Aib-OH TFA
Overview

Fmoc-His-Aib-OH TFA
Fmoc-His-Aib-OH TFA
CAS: 1446013-08-6
Cat. No. : LK0066
M. W. : 576.53
Synonyms: (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid trifluoroacetic acid
IUPAC Name: 2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-2-methylpropanoic acid;2,2,2-trifluoroacetic acid
InChIKey: HKIYFCVPNDIRNF-GKNLIIIVNA-N
SMILES: C(C(O)=O)(F)(F)F.C(OC(N[C@@H](CC1=CN=CN1)C(NC(C(O)=O)(C)C)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3
Documents:
Product Use

Fmoc-His-Aib-OH TFA (CAS: 1446013-08-6), as a part of main chain of semaglutide, can be used as a starting material for the synthesis of semaglutide, this product inserts histidine and modified amino acids (alanine → α-aminoisobutyric acid, resistant to DPP-4 degradation) at the 7th and 8th positions of semaglutide, respectively.

Product Specification

High Purity and Content: individual impurity < 0.1%.

GMP-Compliant Manufacturing: manufactured and released by an GMP-certified API facility. Large production capacity, exceeding 100 killograms per batch.

Comprehensive Quality Studies: able to perform comprehensive quality studies according to the client's requirements, including related substances, residual solvents, genotoxic impurities, inorganic impurities, structure identification, and stability testing, etc. All the methods are well validated and can be transferred to clients. The related impurity references can also be provided.

General Information
Safety & Regulations
Catalog Number LK0066
Purity ≥ 99.0%
Molecular Formula C27H27F3N4O7
Physical State Powder or Crystals
Storage Recommended storage temperature: -20℃, Keep refrigerated and sealed.
Molecular Weight 576.53
CAS NO. 1446013-08-6
GHS Pictogram Fmoc-His-Aib-OH TFA
Signal Word Danger
Hazard Statements H318 (100%)
Precautionary Statements P264+P265, P280, P305+P354+P338, and P317
Product Relate